As a microbiologist and academic lecturer, I have been working on microorganisms that are related to human and health issues. Relatively, I have been interested in the development of bacteria  resistance against chemotherapeutic  agents  which  is  becoming  an  increasing  problem  specially  the  Multi  Drugs  Resistant Bacteria (MDR), and this had the potential to facilitate more rational thinking about the implementation of Bacteriophages as integrated therapeutically framework. I have been working on the environmental impacts of microorganisms that are related to new industrial issues. Also I have been interested on the microorganisms that inhabit, create, or contaminate food, food-safety and their products which can be used to combat pathogenic microbes. In recent years, much interest has been shown in the use of bacteria as probiotic organisms and their potential for disease prevention in humans and animals.

  Research Interest: Microbiology

Research Interest: Environmental Biotechnology including: Assessment of Genetic Diversities; Phytosanitary, Uses of Rhizobacteria in Phytoremediation

Research Interest: Biochemistry, Neurobiology,Laboratory Medicine, Clinical Biochemistry, Clinical Molecular Biology

Degree: Ph.D. in Biology / zoology

Birth: / Iraq / 6 - 10 – 1984

Research Interest: Biology , Zoology , microbiology, parasitology , parasitic diseases, infectious diseases, Biotechnology.

URL: https://www.researchgate.net/profile/Hiba_Riyadh_Jameel
https://scholar.google.com/citations?user=dArfA_cAAAAJ&hl=ar
https://publons.com/researcher/1570960/hiba-al-abodi/

List of Publications: 33

Research Interest: Molecular Biology of non-coding Repetitive DNA: role of satellite DNAs and their transcripts in genome dynamic.

Doctorate in Biotechnology from the Federal University of Bahia (UFBA) of the Northeast BiotechnologyNetwork (RENORBIO), Master in Biotechnology from UFBA, specialization in innovation and quality from thePortuguese Industrial Association, Degree in Biotechnological Engineering from the Lusófona University ofHumanities and Technologies, Bachelor's Degree in Biotechnology by the Higher Institute of Humanities andTechnology. Post-doctorate at the Federal University of Bahia in Biotechnology in the study of photo-stimulation strategies for the production of bioactives included in the project: Sustainable BiotechnologicalAlternatives to Increase the Oil Recovery Factor from Carbonatic Reservoirs, financed by Petrogal. Professionalexperience in the areas of sanitary engineering, industrial biotechnology, environmental biotechnology andmicrobiology. Acting mainly in the following sectors: sanitary, environmental and in the development ofsustainable bioprocesses, to obtain bioactives for industry, involving photo-biomodulation techniques.Production and characterization of photo-stimulated microbial biopolymers reusing industrial co-products.Expertise in research and teaching in the areas of biotechnology, biophotonics, microbiology, chemistry andpharmaceuticals. I currently develop professional activity as a researcher at the Mountain Research Center(CIMO) of the Polytechnic Institute of Bragança, under the ¿OleaChain¿ project, application code NORTE-06-3559-FSE-000188.

Research Interests:

- Biophotomodulation

- Antimicrobial photodynamic therapy

- Photostimulation of bioprocesses

Kevin O. Ochwedo is a molecular biologist with a passion for improving people's health and well-being by participating in programs aimed at malaria transmission reduction and eradication. He is actively involved in genetic epidemiology and entomological studies of parasites and vectors. His most recent publication on Plasmodium falciparum passive surveillance aims to persuade public health policymakers to supplement microscopic examination of blood samples with ultrasensitive diagnostic tools in order to support WHO's strategy of early detection and treatment of malaria patients. This, he believes, will help reduce the large number of untreated patients with false-negative malaria diagnoses who may be acting as a reservoir for P. falciparum transmission to vectors within malaria endemic zones in Sub-Saharan Africa.

List of Publications:

1.    Kevin O. Ochwedo., Collince J.  Omondi., Edwin O. Magomere., Julius O. Olumeh., Isaiah Debrah., Shirley A. Onyango., Pauline W. Orondo., Benyl M. Ondeto., Harrysone E. Atieli., Sidney O. Ogolla., John Githure., Antony C. A. Otieno., Andrew K. Githeko., James W. Kazura., Wolfgang R. Mukabana & Guiyun Yan. (2021). Hyper-prevalence of submicroscopic Plasmodium falciparum infections in a rural area of western Kenya with declining malaria cases. (Under review at Malaria Journal).

2.    Kevin O. Ochwedo., Shirley A. Onyango., Collince J.  Omondi., Pauline W. Orondo., Benyl M. Ondeto., Ming-Chieh Lee., Harrysone E. Atieli., Sidney O. Ogolla., Andrew K. Githeko., Antony C. A. Otieno., Wolfgang R. Mukabana., Guiyun Yan., Daibin Zhong & James W. Kazura. (2022). Signatures of selection and drivers for novel mutation on transmission-blocking vaccine candidate Pfs25 gene in western Kenya. (Under review at PLOS ONE).

3.    Kevin O. Ochwedo., Fredrick O. Ariri., Sidney O. Ogolla., Wolfgang R. Mukabana., Andrew K. Githeko., Yan Guiyan., Daibin Zhong & James W. Kazura. (2022). High frequency of rare alleles and signatures of selection on immunodominant domains of Pfs230 and Pfs48/45 in western Kenya.

4.    Debrah, I., Afrane, Y. A., Amoah, L. E., Ochwedo, K. O., Mukabana, W. R., Zhong, D., ... & Yan, G. (2021). Larval ecology and bionomics of Anopheles funestus in highland and lowland sites in western Kenya.

5.    Orondo, P., Nyanjom, S., Atieli, H., Githure, J., Ondeto, B., Ochwedo, K., ... & Yan, G. (2021). Insecticide Resistance Status of Anopheles Arabiensis in Irrigated and Non-irrigated Areas in Western Kenya.

6.    Ndwiga, L., Osoti, V., Ochwedo, K. O., Wamae, K., Bejon, P., Rayner, J. C., ... & Ochola-Oyier, L. I. (2021). The Plasmodium falciparum Rh5 invasion protein complex reveals an excess of rare variant mutations. Malaria Journal, 20(1), 1-10.

7.    Shirley A. Onyango., Kevin O. Ochwedo., Maxwell G. Machani., Collince J. Omondi., Isaiah Debrah., Sidney O. Ogolla., Ming-Chieh Lee., Goufa Zhou., Elizabeth Kokwaro., Yaw A. Afrane., Andrew K. Githeko., James W. Kazura, Daibin Zhong & Guiyun Yan. (2021). Genetic diversity and population structure of the human malaria parasite Plasmodium falciparum surface protein Pfs47 in isolates from the lowlands in western Kenya.

8.    Shirley A. Onyango., Kevin O. Ochwedo., Maxwell G Machani., Collince J. Omondi., Isaiah Debrah., Sidney O. Ogolla., Ming-Chieh Lee., Goufa Zhou., Elizabeth Kokwaro., Yaw Afrane., James W. Kazura., Andrew K. Githeko., Daibin Zhong & Guiyun Yan. (2022). Molecular Characterization and Genotype Distribution of Thioester-containing protein 1 Gene, A Key Regulator of Malaria Transmission in Anopheles gambiae mosquitoes in Western Kenya.

9.    Benyl M. Ondeto., Xiaoming Wang., Daibin Zhong., Harrysone Atieli., Guofa Zhou., Ming-Chieh Lee., Pauline Orondo., Kevin Ochwedo., Collince J. Omondi., Simon M. Muriu., David Odongo., Horace Ochanda., James Kazura., Andrew Githeko & Guiyun Yan. (2022). Malaria vector bionomics and transmission in irrigated and non-irrigated sites in western Kenya. (Due for submission).

10.    Collince Jared Omondi, Otambo O Wilfred, David Odongo, Kevin O. Ochwedo, Antony Otieno, Shirley A. Onyango, Pauline Orondo, Benyl M. Ondeto, Ming-Chieh Lee, Daibin Zhong, James W. Kazura, Andrew K. Githeko, & Guiyun Yan (2022). Asymptomatic and submicroscopic Plasmodium infections in an area before and during integrated vector control in Homa Bay, western Kenya.

11.    Wilfred Ouma Otambo, Julius O. Olumeh, Kevin O. Ochwedo, Edwin O. Magomere, Isaiah Debrah, Collins Ouma, Patrick Onyango, Harrysone Atieli, Chloe Wang, Ming-Chieh Lee, Andrew K. Githeko, Guofa Zhou, John Githure, James W Kazura, Guiyun Yan & Wolfgang R Mukabana (2022). Health care providers practices in diagnosis and treatment of malaria in rural communities in Kisumu County, Kenya.

Skype ID: kevinochwedo

Doris, is a Professor in the Exact Natural Sciences and Statistics, Faculty of Basic Sciences at University of Santiago of Cali, where he has been since last August. From 2012 to 2018 she was member of Systematic Molecular Group at National University of Colombia. From 2008 to 2012 she was member of Molecular Microbiology Group at Antioquia University. Both universities are located in Colombia. She has explored entomological parameters, molecular taxonomy and infection by Plasmodium of some Anopheles’ vectors. She has also investigated the presence and implications of mosquitoes in High altitude Ecosystem Mountains in Colombia.

Research Interest: Ambient microbiology, Integrative taxonomy and Evolution.

Rosero-García D, Rúa-Uribe G, Correa M, Conn JE, Uribe-Soto S. 2018. Mosquito (Diptera: Culicidae) grouping by OTUs (Operational Taxonomic Units) based on larval habitats characteristics in High Mountain Ecosystems of Antioquia, Colombia. Journal of Vector Ecology 43 (1): 71-79

Rosero-García D, Suaza-Vasco JD, Barajas-Galindo J, Uribe-Soto S. 2017. Mosquito fauna (Diptera: Culicidae) of high Andean mountain ecosystems in Colombia. International Journal of Mosquito Research 4(6): 10-24

Rosero-García D, Bickersmith S, Suaza-Vasco JD, Porter C, Correa M, Conn JE, Uribe-Soto S. 2017. Molecular Operational Taxonomic Units (MOTUs) of mosquitoes collected in high Andean mountain ecosystems from Antioquia, Colombia. Zootaxa 4277 (3): 369–385

Rosero-García D, Suaza-Vasco JD, Uribe-Soto S. 2016. Mosquitos (Diptera: Culicidae) del Páramo de Santa Inés en Belmira, Antioquia: actualización de registros y fortalecimiento de colecciones entomológicas de ecosistemas de alta montaña del MEFLG. Boletín del Museo Entomológico Francisco Luís Gallego 8(2): 6-20

Rosero DA, Naranjo N, Álvarez N, Cienfuegos A, Torres C, Luckhart S, Correa M. 2013. Colombian Anopheles triannulatus (Diptera: Culicidae) naturally infected with Plasmodium spp. ISRN Parasitology, Volumen 2013, Article ID 927453

Naranjo N, Rosero D, Rua G, Luckhart S, Correa M. 2013. Abundance, behavior and entomological inoculation rates of antropophilic anopheline from the Urabá, Bajo Cauca and Alto Sinú region of Colombia. Parasites & Vectors 6:61

Cadavid I, Rosero D, Uribe S. 2013. Comparación de dos métodos de extracción de ADN a partir de plantas del género Solanum, subgénero Leptostemonum. Revista Colombiana de Biotecnología. 15(2): 186-192

Rosero DA, Jaramillo LM, Gutiérrez LA, Conn JE, Correa MM. 2012. Genetic diversity of Anopheles triannulatus s.l. (Diptera: Culicidae) from northwestern and southeastern Colombia. The American Journal Tropical Medicine and Hygiene 87(5):910-920

Cienfuegos AV, Rosero D, Naranjo N, Luckhart S, Conn JE, Correa MM. 2011. Evaluation of a PCR–RFLP–ITS2 assay for discrimination of Anopheles species in northern and western Colombia. Acta Trópica 118: 128–135

Álvarez N, Rosero D, Gómez G, Correa M. 2011. Detección de mosquitos Anopheles infectados naturalmente con Plasmodium spp. en Puerto Libertador, Córdoba, Colombia. Hechos Microbiológicos 2(2); 29-39

Sánchez J, Galeano Y, Rosero D, Naranjo N, Correa M. 2011. Confirmación molecular de especie en especímenes Anopheles recolectados en el corregimiento de Juan José, Puerto Libertador, Córdoba, Colombia. Hechos Microbiológicos 2(1):19-28

Rosero D, Gutiérrez L, Cienfuegos V, Jaramillo L, Correa M. 2010. Optimización de un procedimiento de extracción de ADN para mosquitos anofelinos. Revista Colombiana de Entomología 36(2): 260-26

Gutiérrez LA, González JJ, Castro MI, Gómez GF, Rosero DA, Luckhart S, Conn JE, Correa MM. 2009. Species composition and natural infectivity of anthropophilic Anopheles (Diptera: Culicidae) in the states of Córdoba and Antioquia, northwestern Colombia. Memorias do Instituto Oswaldo Cruz, 104(8): 1117-1124

Rosero D, del Corral H. 2009. Guía sobre cómo hacer una monografía tomando elementos metodológicos utilizados en la revisión sistemática de un tema. Reimpresos Universidad de Antioquia. ISBN: 978-958-714-287-7

Rosero D, del Corral H. Contribución del Análisis RFLP del IS6110 del Mycobacterium tuberculosis al diseño y refinamiento de estrategias para el control de la tuberculosis en Colombia. Infectio 2008, 12(3):175-191

Skype ID: roserodorismb

I am a molecular biologist who specialises in controlling insects that spread deadly or debilitating diseases like malaria, dengue, and zika.  After studying in Brazil, I received my training at the Liverpool School of Tropical Medicine - LSTM and in 2015 was awarded PhD in Tropical Medicine from the University of Liverpool.  After graduation, I returned to Brazil to set up and lead a research group at the Universidade Estadual da Paraíba - UEPB. Currently, my group focused on identifying genetic mutations that arise when mosquitoes develop resistance to the insecticides we use to control them. This forms part of a country-wide disease management strategy, and the results we generate are used to monitor populations for developing resistance, which directly feeds back to the ministry of health decision-makers. Recently, I re-join the Department Vector Biology at LSTM as associate researcher / Wellcome Trust fellow where now I lead a project, which addresses the impact of insecticide resistance and adaptation of Aedes aegypti mosquitoes and how this contributes to their transmission of arboviral diseases in Brazil.

Research Interest: Evolutionary Genetics of insecticide resistance, Vector-borne diseases and integrative approaches for vector control.

Grants:

A.    Wellcome Trust Fellowship - Training Fellowship in Public Health and Tropical Medicine / Liverpool School of Tropical Medicine. 2018-2022 -Funded: £ 312,914, (PI).

B.    Genômica da resistência a inseticidas químicos: impacto no controle de populações do mosquito Aedes aegypti no estado da Paraíba. 2018-2020. Funding: PROPESQ/UEPB, R$: 15,000.00 - Grant number: 2.08.04.00-8-389, (PI).

C.    Entomologial investigation to access vectorial competence and risk of ZIKV amplification in Pernambuco state. 2016-2018. Funding: FACEPE. R$: 192,000.00, (Co-PI).

D.    Thermal ecology of Aedes aegypti (Diptera: Culicidae): implication for development and adaptation. PROPESQ/UEPB. 2016-2018. Funded: R$10,000.00, (Co- PI).

E.    Developing a molecular diagnostic method to identify simultaneous infections of Zika, dengue and chikungunya in field-caught Aedes aegypti mosquitoes using qPCR-multiplex. UEPB. 2016-2018. Funded: R$ 350,000.00, (Co-PI).

F.    Personal PhD fellowship. Coordination for the Improvement of Higher Education Personnel (CAPES). 2012-2015. Funded: £ 163,000.00, (PI).

G.    Spatial-temporal genetic diversity in Aedes aegyptipopulations from Campina Grande, Brazil. PROPESQ/UEPB. 2010-2012. Funded: R$ 15,000.00, (PI).

H.    Effect of temperature in Aedes aegypti (L.) (Diptera: Culicide) populations and Dermestes maculatus DeGeer (Coleoptera: Dermestidae) from three mesoregion of the Paraíba State: Implications for medical and forensic entomology. 2010-2012. PROPESQ/UEPB. Funded: R$ 40,000.00, (Co- PI, 50% ownership).

I.    Georeference and population genetics in Aedes (Stegomyia) aegypti (L.) (Diptera: Culicidae) resistant to temephos. 2008-2010. PROPESQ/UEPB. Funded: R$ 15,000.00, (Co- PI).

J.    Determinant factors for density and permanence of Aedes(Stegomyia) aegypti in urban environment in Paraíba State. OMS/OPAS. 2005-2008. Grant award to UEPB,__BR/LOA/050008.001/2005; R$ 50.000,00, (Co-PI).

K.    Personal Masters` fellowship. 2004-2006. Coordination for the Improvement of Higher Education Personnel (CAPES). Funded: R$24,000.00, (PI).

URL:  http://lattes.cnpq.br/5980156167015578

List of Publications:

A.     Martins, W F. S., Pereira, B. N. S., Alves, A. T. V., Murphy, A., Martins, P. G. S., David Weetman, Craig Stephen Wilding6, Martin James Donnelly. (2019) Development and Application of a Tri-allelic PCR Assay for Screening Vgsc-L1014F Kdr Mutations Associated with Pyrethroid and Organochlorine Resistance in the Mosquito Culex quinquefasciatus. Parasites & Vectors, 201912:232. 

B.       Martins, W. F. S., Wilding, C. S., Isaacs, A. T., Rippon, E. J., Mawejje, H. D., Megy, K., Donnelly. M. J. (2018) Transcriptomic analysis of insecticide resistance in the lymphatic filariasis vector Culex quinquefasciatus. bioRxiv 589028; doi: https://doi.org/10.1101/589028 Scientific Reports, under review.

C.    Martins, W. F. S., Wilding, C. S., Steen, K., Mawejje, H., Antão, T. R., Donnelly, M. J. (2017) Local selection in the presence of high levels of gene flow: Evidence of heterogeneous insecticide selection pressure across Ugandan Culex quinquefasciatus populations. PLOS Neglected Tropical Diseases, 11(10), p.e0005917.

D.    Martins, W. F. S., Subramaniam, K., Steen, K., Mawejje, H., Liloglou, T., Wilding, C. S., Donnelly, M. J. (2017) Comparative Analysis Methods for Inference of Copy Number Variation in the Voltage-gated Sodium Channel Gene of Culex quinquefasciatus Mosquitoes. Scientific Reports, 7(1), p.5821.

E.    Steffler, L. M., Dolabella, S. S., Ribolla, P. E. M., Dreyer, C. S., Araujo, E. D., Oliveira, R. S., Martins, W. F. S., Santos, R. La. C. S. (2016) Genetic variability and spatial distribution in small geographic scale of Aedes aegypti (Diptera: Culicidae) under different climatic conditions in Northeastern Brazil. Parasites and Vectors, 9:530. DOI 10.1186/s13071-016-1814-9.

F.    Gambarra, W. P. T., Martins, W. F. S., Filho, M. L. De L., Albuquerque, I. M. C. De., Apolinário, O. K. Dos S., Beserra, E. B. (2013) Spatial distribution and esterase activity in populations of Aedes (Stegomyia) aegypti (Linnaeus) (Diptera: Culicidae) resistant to temephos. Revista da Sociedade Brasileira de Medicina Tropical 46, p. 178-178.

G.    Castro Jr, F. P. De ., Martins, W. F. S.; Filho, M. L. De L., Almeida, R. P. De.; Beserra, E. B. (2013) Ciclos de vida comparados de Aedes aegypti (Diptera, Culicidae) do semiárido da Paraíba. Iheringia. Série Zoologia. 103, p. 118-123.

My name is Guichuan Lai, a medical doctor, currently working in the department of health statistics at Chongqing Medical University. I have published 16 SCI papers in the past 2 years, and served as a longtime reviewer for Frontiers, BMC, Springer, and the Elsevier. My research area is exploring biomarkers of diseases using bioinformatics and network science methods, including single-cell sequencing technology, network medicine technology, and machine learning methods. Finally, I hope to be able to create value for the journal through my own experience. Here are the SCI articles I have published in the last two years:

Research Interests:

My research interest is exploring biomarkers of diseases using bioinformatics and network science methods, including single-cell sequencing technology, network medicine technology, and machine learning methods.

List of Publications:

1. Lai G, Li K, Deng J, Liu H, Xie B, Zhong X. Identification and Validation of a Gene Signature for Lower-Grade Gliomas Based on Pyroptosis-Related Genes to Predict Survival and Response to Immune Checkpoint Inhibitors. J Healthc Eng. 2022 Apr 30;2022:8704127. doi: 10.1155/2022/8704127. PMID: 35535221; PMCID: PMC9078805.
2. Lai G, Liu H, Deng J, Li K, Xie B. A Novel 3-Gene Signature for Identifying COVID-19 Patients Based on Bioinformatics and Machine Learning. Genes (Basel). 2022 Sep 8;13(9):1602. doi: 10.3390/genes13091602. PMID: 36140771; PMCID: PMC9498787.
3. Lai G, Zhong X, Liu H, Deng J, Li K, Xie B. Development of a Hallmark Pathway-Related Gene Signature Associated with Immune Response for Lower Grade Gliomas. Int J Mol Sci. 2022 Oct 9;23(19):11971. doi: 10.3390/ijms231911971. PMID: 36233273; PMCID: PMC9570050.
4. Lai G, Zhong X, Liu H, Deng J, Li K, Xie B. A Novel m7G-Related Genes-Based Signature with Prognostic Value and Predictive Ability to Select Patients Responsive to Personalized Treatment Strategies in Bladder Cancer. Cancers (Basel). 2022 Oct 29;14(21):5346. doi: 10.3390/cancers14215346. PMID: 36358764; PMCID: PMC9656096.
5. Lai G, Liu H, Deng J, Li K, Zhang C, Zhong X, Xie B. The Characteristics of Tumor Microenvironment Predict Survival and Response to Immunotherapy in Adrenocortical Carcinomas. Cells. 2023 Feb 27;12(5):755. doi: 10.3390/cells12050755. PMID: 36899891; PMCID: PMC10000893.
6. Chi H, Xie X, Yan Y, Peng G, Strohmer DF, Lai G, Zhao S, Xia Z, Tian G. Natural killer cell-related prognosis signature characterizes immune landscape and predicts prognosis of HNSCC. Front Immunol. 2022 Oct 3;13:1018685. doi: 10.3389/fimmu.2022.1018685. PMID: 36263048; PMCID: PMC9575041.
7. Zhao S, Zhang L, Ji W, Shi Y, Lai G, Chi H, Huang W, Cheng C. Machine learning-based characterization of cuprotosis-related biomarkers and immune infiltration in Parkinson's disease. Front Genet. 2022 Oct 17;13:1010361. doi: 10.3389/fgene.2022.1010361. PMID: 36338988; PMCID: PMC9629507.
8. Zhao S, Chi H, Ji W, He Q, Lai G, Peng G, Zhao X, Cheng C. A Bioinformatics-Based Analysis of an Anoikis-Related Gene Signature Predicts the Prognosis of Patients with Low-Grade Gliomas. Brain Sci. 2022 Oct 5;12(10):1349. doi: 10.3390/brainsci12101349. PMID: 36291283; PMCID: PMC9599312.
9. Zhao S, Ji W, Shen Y, Fan Y, Huang H, Huang J, Lai G, Yuan K, Cheng C. Expression of hub genes of endothelial cells in glioblastoma-A prognostic model for GBM patients integrating single-cell RNA sequencing and bulk RNA sequencing. BMC Cancer. 2022 Dec 6;22(1):1274. doi: 10.1186/s12885-022-10305-z. PMID: 36474171; PMCID: PMC9724299.
10. Xie B, Li K, Zhang H, Lai G, Li D, Zhong X. Identification and validation of an immune-related gene pairs signature for three urologic cancers. Aging (Albany NY). 2022 Feb 10;14(3):1429-1447. doi: 10.18632/aging.203886. Epub 2022 Feb 10. PMID: 35143414; PMCID: PMC8876921.
11. Liu H, Lai G, Shi G, Zhong X. The Influencing Factors of HIV-Preventive Behavior Based on Health Belief Model among HIV-Negative MSMs in Western China: A Structural Equation Modeling Analysis. Int J Environ Res Public Health. 2022 Aug 17;19(16):10185. doi: 10.3390/ijerph191610185. PMID: 36011822; PMCID: PMC9407807.
12. Chi H, Peng G, Yang J, Zhang J, Song G, Xie X, Strohmer DF, Lai G, Zhao S, Wang R, Yang F, Tian G. Machine learning to construct sphingolipid metabolism genes signature to characterize the immune landscape and prognosis of patients with uveal melanoma. Front Endocrinol (Lausanne). 2022 Dec 8;13:1056310. doi: 10.3389/fendo.2022.1056310. PMID: 36568076; PMCID: PMC9772281.
13. Zhang Z, Lai G, Sun L. Basement-Membrane-Related Gene Signature Predicts Prognosis in WHO Grade II/III Gliomas. Genes (Basel). 2022 Oct 7;13(10):1810. doi: 10.3390/genes13101810. PMID: 36292695; PMCID: PMC9602375.
14. Zhao S, Chi H, Yang Q, Chen S, Wu C, Lai G, Xu K, Su K, Luo H, Peng G, Xia Z, Cheng C, Lu P. Identification and validation of neurotrophic factor-related gene signatures in glioblastoma and Parkinson's disease. Front Immunol. 2023 Feb 7;14:1090040. doi: 10.3389/fimmu.2023.1090040. PMID: 36825022; PMCID: PMC9941742.
15. Zhang Y, Zhang C, Li K, Deng J, Liu H, Lai G, Xie B, Zhong X. Identification of Molecular Subtypes and Prognostic Characteristics of Adrenocortical Carcinoma Based on Unsupervised Clustering. Int J Mol Sci. 2023 Oct 23;24(20):15465. doi: 10.3390/ijms242015465. PMID: 37895143; PMCID: PMC10607826.
16. Gut microbiome dysbiosis in men who have sex with men increase HIV infection risk through immunity homeostasis alteration (Waiting for publication)

Research Interest: Tumor Biology - Progression Factors

I have completed my PhD from National Institute of Immunology, New Delhi, India in 2016 in microbiology and molecular biology feild. Soon after that I have joined Weill Cornell Medical College, New York in June 2016 and working in the field of metabolomics to understand the immunological insults and adaptations happening during TB infection. I have identified various metabolic signatures and important mechanism to enhance the therapeutic potential of anti-TB drugs and therapies. I am expert in microbiology, genetic engineering, metabolomics, molecular biology, drug target identification, drug screening, drug development, in vivo drug testing and identification of metabolic bio-signature (Biomarkers).

Research Interest: Microbiology, Immunology, Metabolomics, Metabolism, Drug Development, Assay Development, and Molecular biology

URL: https://www.linkedin.com/in/vijay-soni-ph-d-3271a581

List of Publications:

First author papers: Total 3
1. Soni V, Upadhayay S, Suryadevara P, Samla G, Singh A, Yogeeswari P, Sriram D, Nandicoori VK. Depletion of M. tuberculosis GlmU from Infected Murine Lungs Effects the Clearance of the Pathogen. PLoS Pathog. 2015 Oct 21;11(10):e1005235.

2. Soni V, Suryadevara P, Sriram D; OSDD Consortium, Kumar S, Nandicoori VK, Yogeeswari P. Structure-based design of diverse inhibitors of Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase: combined molecular docking, dynamic simulation, and biological activity. J Mol Model.2015 Jul;21(7):2704.

3. Jagtap PK, Soni V*, Vithani N, Jhingan GD, Bais VS, Nandicoori VK, Prakash B. Substrate-bound crystal structures reveal features unique to Mycobacterium tuberculosis N-acetyl-glucosamine 1-phosphate uridyltransferase and a catalytic mechanism for acetyl transfer. J Biol Chem. 2012 Nov 16;287(47):39524-37. * First Co-author.

Middle author papers: Total 9
4. Suryadevara P, Yogeeswari P, Soni V, Devi PB, Nandicoori VK, Sriram D. Computational Sampling and Simulation Based Assessment of Novel Mycobacterium tuberculosis Glutamine Synthetase Inhibitors: Study involving Structure Based Drug Design and Free Energy Perturbation. Curr Top Med Chem. 2015 Aug 25.

5. Parthiban Brindha Devi, Jonnalagadda Padma Sridevi, Shruti Singh Kakan, Shalini Saxena, Variam Ullas Jeankumar, Vijay Soni, Hasitha Shilpa Anantaraju, Perumal Yogeeswari, Dharmarajan Sriram. Discovery of novel lysine ɛ-aminotransferase inhibitors: An intriguing potential target for latent tuberculosis. Tuberculosis. 2015, PII:S1472-9792 (15)20720-2

6. Petersen GO, Saxena S, Renuka J, Soni V, Yogeeswari P, Santos DS, Bizarro CV, Sriram D. Structure-based virtual screening as a tool for the identification of novel inhibitors against Mycobacterium tuberculosis 3-dehydroquinate dehydratase. J Mol Graph Model.2015 May 11.

7. Pulla VK, Sriram DS, Soni V, Viswanadha S, Sriram D, Yogeeswari P. Targeting NAMPT for Therapeutic Intervention in Cancer and Inflammation: Structure-Based Drug Design and Biological Screening. ChemBiol Drug Des.2015 Apr 7.

8. Sridevi JP, Suryadevara P, Janupally R, Sridhar J, Soni V, Anantaraju HS, Yogeeswari P, Sriram D. Identification of potential Mycobacterium tuberculosis topoisomerase I inhibitors: a study against active, dormant and resistant tuberculosis. Eur J Pharm Sci. 2015 May 25;72:81-92.

9. Janupally R, Jeankumar VU, Bobesh KA, Soni V, Devi PB, Pulla VK, Suryadevara P, Chennubhotla KS, Kulkarni P, Yogeeswari P, Sriram D. Structure-guided design and development of novel benzimidazole class of compounds targeting DNA gyraseB enzyme of Staphylococcus aureus. Bioorg Med Chem. 2014 Nov 1;22(21):5970-87..

10. Jeankumar VU, Renuka J, Pulla VK, Soni V, Sridevi JP, Suryadevara P, Shravan M, Medishetti R, Kulkarni P, Yogeeswari P, Sriram D. Development of novel N-linked aminopiperidine-based mycobacterial DNA gyrase B inhibitors: scaffold hopping from known antibacterial leads. Int J Antimicrob Agents.2014 Mar;43(3):269-78.

11. Saxena S, Devi PB, Soni V, Yogeeswari P, Sriram D. Identification of novel inhibitors against Mycobacterium tuberculosis L-alanine dehydrogenase (MTB-AlaDH) through structure-based virtual screening. J Mol Graph Model.2014 Feb;47:37-43.

12. Jeankumar VU, Renuka J, Santosh P, Soni V, Sridevi JP, Suryadevara P, Yogeeswari P, Sriram D. Thiazole-aminopiperidine hybrid analogues: design and synthesis of novel Mycobacterium tuberculosis GyrB inhibitors. Eur J Med Chem. 2013;70:143-53.

Patent:
13.  Indian patent; Status: Filed; File no: 3167/DEL/2015 Title: Depletion of M. tuberculosis GlmU from Infected Murine Lungs Effects the Clearance of the Pathogen.
Authors: Vinay K Nandicoori, Vijay Soni, Perumal Yogeeswari and Dharamarajan Sriram.

Research Interest: Biochemistry and Biotechnology (Wastewater Treatment, Biomass Growth, Kinetic Growth Study, Microalgae, Enzymatic Technology, Advanced Oxidation Processes, Adsorption, Ion Exchange, Membrane Technology).

Research Interest: Cardiovascular Diseases, Neurology, Ischemic Stroke, Oxidative Stress, Antioxidant System,Immune System, Inflammation, Synaptic Plasticity, Molecular and Cellular Biology, Two-Photon Microscop.

Research Interest: Signal Transduction, Steroid Hormones,Anti-Cancer Activities,Resveratrol and Derivatives