The Preliminary Study on the Effect of Mongolian Milkvetch Root Extract Containing Cycloastragenol on Telomere Length in Myanmar People

Khin Maung Lwin, Aye Aye*, Hlaing Hlaing Oo and Lwin Mon Mon Myint*

Telomere shortening is a primary hallmark of biological aging and is influenced by factors such as nutritional status and psychological stress. The effects of RejuMax, a nutritional supplement containing cycloastragenol derived from Mongolian milkvetch root extract, on telomere length in the Myanmar population had not been previously investigated. This study evaluated the impact of RejuMax supplementation on telomere length in healthy middle-aged adults in Myanmar. A total of 10 participants (mean age: 50.1 ± 10.3 years) were enrolled, including four men (mean age: 51.5 ± 13.8 years) and six women (mean age: 49.1 ± 8.5 years). Participants received RejuMax supplementation for six months, followed by a six-month washout period. Average telomere length (TL) was measured at baseline, after six months of supplementation, and after the washout period using the qPCR method. RejuMax supplementation was well tolerated, and no adverse events were reported during the study. A statistically significant increase in TL was observed following the six-month supplementation period (p < 0.05). However, telomere length declined toward baseline values during the subsequent washout phase, suggesting that the observed effects may not be sustained in the absence of continued supplementation. 

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Published on: Aug 1, 2026 Pages: 9-13

Full Text PDF Full Text HTML DOI: 10.17352/jbm.000050
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